Several factors that predict the outcome of large B‐cell lymphoma patients who relapse/progress after chimeric antigen receptor (<scp>CAR</scp>) T‐cell therapy can be identified before cell administration
Our findings allow better stratification of CAR-Tx candidates and stress the need for a proactive approach (earlier restaging, intervention after partial remission achievement).
Authors
- T. Jancarkova
- Ľuboš Drgoňa (ORCID: https://orcid.org/0000-0002-5089-3201)
- Adriana Heindorfer
- Eva Čermáková (ORCID: https://orcid.org/0000-0003-3413-4149)
- Kateřina Steinerová
- Alice Šýkorová (ORCID: https://orcid.org/0000-0002-8773-6250)
- Andrea Janíková (ORCID: https://orcid.org/0000-0002-2647-7769)
- Kamila Polgárová (ORCID: https://orcid.org/0000-0003-2822-1692)
- Jan Vydra (ORCID: https://orcid.org/0000-0002-4274-3895)
- Andrej Vranovský
- Ivana Plameňová
- Juraj Ďuraš
- Aleš Obr (ORCID: https://orcid.org/0000-0002-6758-3074)
- David Belada (ORCID: https://orcid.org/0000-0002-4981-6188)
- František Folber (ORCID: https://orcid.org/0000-0001-7034-769X)
- Miriam Ladická
- Robert Pytlík (ORCID: https://orcid.org/0000-0002-0517-2691)
- Heidi Móciková (ORCID: https://orcid.org/0000-0003-2034-0769)
- Marek Trněný (ORCID: https://orcid.org/0000-0002-6952-6073)
- Lukáš Smolej (ORCID: https://orcid.org/0000-0002-4187-8595)
- Vít Procházka
- Erika Čellárová
- Martin Sedmina
- L. Lukáčová
- Margaréta Králiková
Institutions
- University of Prešov (SK)
- University of Ostrava (CZ)
- Charles University (CZ)
- Masaryk University (CZ)
- University Hospital Ostrava (CZ)
- Institute of Haematology and Blood Transfusion (CZ)
- University Hospital Brno (CZ)
- Krajská Nemocnice Liberec (CZ)
- University Hospital Hradec Králové (CZ)
- University Hospital Kralovske Vinohrady (CZ)
- Palacký University Olomouc (CZ)
- Comenius University Bratislava (SK)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/cam4.70138
- Citations
- 1
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- Univerzita Karlova v Praze
- Ministerstvo Zdravotnictví Ceské Republiky