Tumor-Infiltrating Lymphocytes in Necrotic Tumors after Melanoma Neoadjuvant Anti–PD-1 Therapy Correlate with Pathologic Response and Recurrence-Free Survival
CD3+ and CD8+ nTIL are associated with pathologic response and 5-year RFS in patients with melanoma after neoadjuvant anti-PD-1 therapy.
Authors
- John T. Miura (ORCID: https://orcid.org/0000-0001-7028-2152)
- David E. Elder (ORCID: https://orcid.org/0000-0003-4575-2364)
- Ravi K. Amaravadi (ORCID: https://orcid.org/0000-0002-5768-2474)
- Tara C. Mitchell (ORCID: https://orcid.org/0000-0002-8186-7284)
- Lynn M. Schuchter
- Ahron Flowers (ORCID: https://orcid.org/0000-0002-5579-1351)
- Phyllis A. Gimotty (ORCID: https://orcid.org/0000-0002-3850-9799)
- Cimarron E. Sharon (ORCID: https://orcid.org/0000-0002-8398-3297)
- Giorgos C. Karakousis (ORCID: https://orcid.org/0000-0002-9321-2795)
- Gabriella N. Tortorello (ORCID: https://orcid.org/0000-0002-1836-6612)
- Eric E. Morgan (ORCID: https://orcid.org/0000-0002-6737-669X)
- Alexander C. Huang (ORCID: https://orcid.org/0000-0002-0099-0492)
- L. Kevin (ORCID: https://orcid.org/0000-0001-8256-3269)
- Xiaowei Xu (ORCID: https://orcid.org/0000-0003-4098-7690)
- Meaghan Dougher
Institutions
- Hospital of the University of Pennsylvania (US)
- California University of Pennsylvania (US)
- Columbia University (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1158/1078-0432.ccr-23-3775
- Citations
- 8
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.26
Funders
- National Institutes of Health