Mirtazapine to alleviate severe breathlessness in patients with COPD or interstitial lung diseases (BETTER-B): an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial
EU Horizon 2020 (grant agreement No. 825319); Cicely Saunders International Breathlessness Programme; National Institute for Health and Care Research Applied Research Collaboration South London; Australian National Health and Medical Research Council-EU (application ID: APP1170731).
Authors
- Sabrina Bajwah (ORCID: https://orcid.org/0000-0001-5338-8107)
- Claudia Bausewein (ORCID: https://orcid.org/0000-0002-0958-3041)
- Peter May (ORCID: https://orcid.org/0000-0001-8501-6500)
- David C. Currow (ORCID: https://orcid.org/0000-0003-1988-1250)
- Matthew M Maddocks (ORCID: https://orcid.org/0000-0002-0189-0952)
- Simon P. Hart (ORCID: https://orcid.org/0000-0003-4606-9559)
- Piotr Janowiak (ORCID: https://orcid.org/0000-0001-7941-465X)
- Andrew Wilcock (ORCID: https://orcid.org/0000-0002-3214-1188)
- Caroline J. Jolley (ORCID: https://orcid.org/0000-0003-3538-2451)
- Silvia Tanzi (ORCID: https://orcid.org/0000-0001-5798-5064)
- Julia Brown (ORCID: https://orcid.org/0000-0002-2719-7064)
- Charles Normand (ORCID: https://orcid.org/0000-0002-0885-5754)
- Massimo Costantini (ORCID: https://orcid.org/0000-0002-5293-7079)
- Małgorzata Krajnik (ORCID: https://orcid.org/0000-0001-9473-6163)
- H M Mather (ORCID: https://orcid.org/0009-0009-7462-4119)
- Charlotte E. Bolton (ORCID: https://orcid.org/0000-0002-9578-2249)
- Elena Turola (ORCID: https://orcid.org/0000-0002-1810-8648)
- Steffen T. Simon (ORCID: https://orcid.org/0000-0002-6884-1813)
- Luca Ghirotto (ORCID: https://orcid.org/0000-0001-7632-1271)
- Miriam J. Johnson (ORCID: https://orcid.org/0000-0001-6204-9158)
- Bobbie Farsides (ORCID: https://orcid.org/0000-0002-5477-0612)
- Adejoke O Oluyase (ORCID: https://orcid.org/0000-0002-1506-7262)
- Geraldine Murden (ORCID: https://orcid.org/0000-0003-3124-9389)
- Irene J Higginson (ORCID: https://orcid.org/0000-0002-3687-1313)
- Karen Ryan (ORCID: https://orcid.org/0000-0001-9149-260X)
- Sarah T Brown
Institutions
- Brighton and Sussex Medical School (GB)
- University of Leeds (GB)
- Nottingham University Hospitals NHS Trust (GB)
- University of Nottingham (GB)
- University of Sussex (GB)
- King's College London (GB)
- University of Hull (GB)
- University of Wollongong (AU)
- Mater Misericordiae University Hospital (IE)
- Nicolaus Copernicus University (PL)
- University of Gdańsk (PL)
- Düsseldorf University Hospital (DE)
- Azienda Sanitaria Unità Locale di Reggio Emilia (IT)
- Integrated Oncology (United States) (US)
- Cicely Saunders International (GB)
- Nottingham Biomedical Research Centre (GB)
- Collegium Medicum in Bydgoszcz (PL)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University Hospital Cologne (DE)
- Heinrich Heine University Düsseldorf (DE)
- Hull York Medical School (GB)
- Gdańsk Medical University (PL)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- The Lancet Respiratory Medicine
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1016/s2213-2600(24)00187-5
- Citations
- 20
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 8.38