EP10.16: Fetoscopic tree ports exteriorised uterus for myelomeningocele repair

The aim of the study was to describe the initial experience of exteriorised-uterus fetoscopic repair (EUFR) for spina bifida (SB) repair and perinatal outcomes. This was a retrospective analysis of collected data in a single centre, that underwent EUFR of SB at our centre, between Jan 2019 and Dec 2020. All patients satisfied the Management of Myelomeningocele Study (MOMS) criteria. Data for 30 patients, all cases have a complete fetoscopic repair were analysed. Maternal demographics and mean gestational age (GA) at fetal surgery (25.2 to 26.6 weeks(w) - median 25.2 w), and at delivery (26 to 39 w–median 34 w+6 days). Duration of surgery 168 minutes (90–120 minutes). The rate of preterm prelabour rupture of membranes PROM (see table 1), mean GA at PPROM (34 w ± 5 days) and rate of vaginal delivery was (31‰). No cases of leakage was reported. Reversal herniation of hindbrain herniation 4-6 weeks after surgery. There were 2 (6,1%) neonatal or perinatal deaths, 1 case PROM after 48 hours of surgery and extreme prematurity, and 1 case at 31 w + 3 days neonatal sepsis. Wound dehiscence requiring postnatal closure was founded in 2 cases, but no leakage. Of the 28 neonates that survived in the first 12 months, 2 cases required either a shunt or endoscopic third ventriculostomy. (F3PEU) repair for neural tubal defects in your series does not show an increase of maternal-fetal complications as compared with classical open surgery, allows vaginal delivery, similar neurologic outcomes and potentially reduce long-term maternal risks. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Authors

Publication Details

Journal
Ultrasound in Obstetrics and Gynecology
Published
2024-09-01
DOI
https://doi.org/10.1002/uog.28511
Primary Topic
Spinal Dysraphism and Malformations
Type
article
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article

EP10.16: Fetoscopic tree ports exteriorised uterus for myelomeningocele repair

Ricardo Arraes de Alencar Ximenes
Ultrasound in Obstetrics and Gynecology
Spinal Dysraphism and Malformations
article

EP10.16: Fetoscopic tree ports exteriorised uterus for myelomeningocele repair

Ricardo Arraes de Alencar Ximenes
article en

Abstract

The aim of the study was to describe the initial experience of exteriorised-uterus fetoscopic repair (EUFR) for spina bifida (SB) repair and perinatal outcomes. This was a retrospective analysis of collected data in a single centre, that underwent EUFR of SB at our centre, between Jan 2019 and Dec 2020. All patients satisfied the Management of Myelomeningocele Study (MOMS) criteria. Data for 30 patients, all cases have a complete fetoscopic repair were analysed. Maternal demographics and mean gestational age (GA) at fetal surgery (25.2 to 26.6 weeks(w) - median 25.2 w), and at delivery (26 to 39 w–median 34 w+6 days). Duration of surgery 168 minutes (90–120 minutes). The rate of preterm prelabour rupture of membranes PROM (see table 1), mean GA at PPROM (34 w ± 5 days) and rate of vaginal delivery was (31‰). No cases of leakage was reported. Reversal herniation of hindbrain herniation 4-6 weeks after surgery. There were 2 (6,1%) neonatal or perinatal deaths, 1 case PROM after 48 hours of surgery and extreme prematurity, and 1 case at 31 w + 3 days neonatal sepsis. Wound dehiscence requiring postnatal closure was founded in 2 cases, but no leakage. Of the 28 neonates that survived in the first 12 months, 2 cases required either a shunt or endoscopic third ventriculostomy. (F3PEU) repair for neural tubal defects in your series does not show an increase of maternal-fetal complications as compared with classical open surgery, allows vaginal delivery, similar neurologic outcomes and potentially reduce long-term maternal risks. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Ultrasound in Obstetrics and GynecologyVol. 64(S1)
Openalex Percentile: Top 77%
Spinal Dysraphism and Malformations
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