EP17.66: Prenatal care strategy using clinical factors for pre‐eclampsia risk prediction and prophylaxis indication

This study evaluated clinical risk factors as a strategy to predict the risk of pre-eclampsia (PE), aiming to identify patients at high-risk for this condition. 145 patients admitted to a Maternity Hospital in São Paulo, diagnosed with hypertensive disorders of pregnancy, were interviewed between 12/2022 and 10/2023. We adopted the definition of PE as provided by the International Society for the Study of Hypertension in Pregnancy. The factors investigated were age, parity, ethnicity, BMI in the first and third trimesters, time since the last pregnancy, previous PE, comorbidities, number of fetuses, IVF, and family history of PE. In Brazil, the recommendations of prophylaxis for PE with aspirin and calcium are based on a risk score created by the Brazilian Network of Studies on Hypertension in Pregnancy, following guidelines of ACOG and NICE-UK. Who have at least one high-risk or two moderate risk factors should receive both drugs. The most statistically significant risk factors (p-value <0.05) were previous chronic hypertension, with a Relative Risk Increase (RRI) of 28.74, and family history of PE (RRI of 2.82). The median BMI in the first trimester for patients with gestational hypertension was 27 (overweight) and for those with PE was 31 (obesity class I). From 145 interviewed, 104 were classified as high-risk for PE, of those, 72 had PE, but only 51 used aspirin and calcium. The main limitation was the lack of data of some patients. Clinical risk factors proved to be a reasonable low-cost device for predicting risk for PE. Prophylaxis should have its importance reinforced in prenatal care, given the insufficient prescriptions and low adherence of patients. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.