OC18.06: Prolapse prevalence declines in the elderly

Higher POP incidence has been demonstrated with advanced age. The natural history of POP, however, is not fully understood. To study associations between age and prevalence of different types of POP. Retrospective study using archived data sets obtained in a tertiary urogynecological centre between 01/2012 and 12/2021. All had undergone an interview, POPQ and TLUS. Associations between age at presentation classified by decade and different types of POP were tested. 3473 data sets were analysed. Mean age was 58 (17-95) years. 89% were vaginally parous. 1805 (52%) presented with POP. 2625 (76%) had a clinically significant cystocele, 1001 (29%) uterine prolapse and 1938 (56%) rectal decent. On TLUS it was 1442 (42%),1001 (29%) and 1435 (41%) respectively. Prevalence of different types of POP of different age groups are shown in table 1. While prevalence of cystocele and uterine POP were significantly associated with patient's age group, this association was not linear. We found generally reduced prevalence in the 8th and 9th decade. Our findings suggest that POP may not necessarily worsen with age. Prevalence of clin sig Ut POP* (%) Prevalence of clin sig rectocele (%) Prevalence of US sig Cystocele (%) Prevalence of US sig Ut POP* (%) Prevalence of US sig rectal descent (%) P = 0.001 OR 0.91 (CI 0.86-0.96) P = 0.42 OR 1.02 (CI 0.97-1.09) P = 0.098 OR 1.04 (CI 0.99-1.09) P = 0.024 OR 1.06 (CI 1.01-1.11) P = 0.027 OR 0.94 (Cl 0.88-0.99) P = 0.567 OR 1.01 (0.97-1.06) P < 0.001 OR 0.87 (CI 0.82-0.93) P = 0.399 OR 0.97 (CI 0.9-1.04) P = 0.811 OR 0.99 (Cl 0.94-1.05) P = 0.071 OR 1.06 (CI 0.99-1.14) P = 0.002 OR 0.89 (CI 0.83-0.96) P = 0.258 OR 0.96 (CI 0.91-1.03)