EP09.111: Ultrasound examination of fetal myocardium to screen out pregnancy complication in gestational diabetes mellitus
Our prospective case-control study of pregnancies complicated by gestational diabetes mellitus(GDM) produce fetal myocardium hyperplasia. We sought the first detecting period of myocardium hyperplasia in GDM. A 2nd (24-28th weeks) and a 3rd (33-38th weeks) trimester ultrasound examinations were carried out on 84 pregnant women, in accordance with the selection criteria (GDM and control cases). During the examinations we measured and averaged the fetal parameters: the estimated fetal weight, the quantity of amniotic fluid and the thickness of the interventricular septum. We compared these data against the our control group and GDM group. Comparing the interventricular septum's average and standard deviation (0,42cm ± 0,13), examined by fetal cardio-ultrasound in gestational weeks 24-28, to the average and standard deviation (0,25cm ± 0,07) of the our control group, we found significant discrepancy (p = 0,045). The interventricular septum's average and standard deviation (0,76cm ± 0,29) examined in gestational weeks 32-38 significantly differs (p < 0,001) from the average and standard deviation (0,36cm ± 0,07) of the our control group. (see figure 1). Based on the examinations we concluded that the second trimester ultrasound presented early significantly alteration in intraventricular septum, while the third trimester ultrasound were more characteristics. Thus, following the fetal myocardium's parameters in the perinatal outcome of the mother's glucose system's discrepancies can be a well-applicable filtering method. Funding: Supported by 'Géza Hetényi' Grant, Medical Faculty Research Fund, University of Szeged (No.:SZTE SZAOK-KKA, IV -3646-62-14/2022 SZAOK) Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Authors
- Andrea Surányi (ORCID: https://orcid.org/0000-0002-1168-7261)
- Zsófia Kádas
- Zoltán Pál
- Gábor Németh (ORCID: https://orcid.org/0000-0003-1829-3457)
- Szabolcs Várbı́ró (ORCID: https://orcid.org/0000-0002-7109-6906)
- Zoltán Kozinszky (ORCID: https://orcid.org/0000-0001-7485-9895)
Institutions
- University of Szeged (HU)
Publication Details
- Journal
- Ultrasound in Obstetrics and Gynecology
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/uog.28492
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Szegedi Tudományegyetem