EP08.12: Fetal adrenal gland volume and thymus gland volume in normal versus growth‐restricted fetuses

This study aimed to determine the association between fetal adrenal gland volume and thymus gland volume and late onset FGR. This case-control study was conducted at a tertiary hospital's obstetrics and gynecology department. The study recruited pregnant women with late onset fetal growth restriction with gestational age ≥ 32 weeks and presented for antenatal care. A control group was recruited, including women with normal pregnancies of the same gestational age. Upon recruitment, fetal adrenal gland volume and medulla width and the thymus gland volume were measured using 3D ultrasound. There was 32 and 36 participants in the study and control groups respectively. Both groups were matched in their primary demographic data. The estimated fetal weight was significantly lower among the fetal growth restriction group than the control group (1786.66 ± 320.35 vs. 2518.75 ± 402.52, respectively. P-value was < 0.001). The adrenal gland volume was significantly higher among fetuses with fetal growth restriction than the control group (384.69 ± 70.79 vs.312.33 ± 62.33, respectively. P-value < 0.001). The thymus gland volume was significantly lower among growth-restricted fetuses (p-value 0.027). When combined together, both markers predicted FGR with a sensitivity and specificity of 72% and 80%, respectively. Fetal adrenal gland volume and thymus gland volume predicted FGR with great sensitivity and specificity. Group 1 (n = 32) Group 2 (n = 36) Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.