EP06.26: Slice‐to‐volume registration to assess lung volume in fetuses with congenital diaphragmatic hernia who underwent fetoscopic enlolunial tracheal occlusion

Retrospective cohort study of 31 fetuses with isolated CDH who underwent FETO. TFLV was measured by MRI before FETO and 6 weeks after FETO on original MRI volumes and after motion artifact correction using SVR (SVRTK). Pearson Correlation (r,p) was used to evaluate the correlation between O/E TFLV obtained using original MRI or SVR volumes. Prediction of 6-month survival based on O/E TFLV obtained using original volumes or after SVR was evaluated using ROC analyses. There were no differences in O/E TFLV measurements using original (24.47[6-52]%) or SVR volumes (25.5[9-49]%, p = 0.07) before FETO or after FETO (33.70[8-116]% vs 32.40[12-76]%, p = 0.17). There was a good agreement for O/E TFLV estimation between original and SVR volumes before FETO (r = 0.75, p < 0.01) and a very good agreement after FETO (r = 0.96, p < 0.01). ROC analysis showed similarities in the prediction of survival after FETO when O/E TFLV was measured using original volumes or SVR volumes (see figure 1). There was a good correlation and comparable postnatal survival prediction between O/E TFLVs measured on original MRI volumes or after SVR. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.