Synthesis of Diaryl Ethers via Hypervalent Iodine-Mediated C–H Functionalization
A hypervalent iodine-reagent-based C-H functionalization strategy was utilized to synthesize diaryl ethers. This method directly transforms various arenes into their corresponding diaryliodonium salts, followed by a C-O coupling reaction to produce structurally diverse diaryl ethers. The efficacy of this approach in the late-stage structural modifications of complex molecules was demonstrated.
Authors
- Yanchuan Zhao (ORCID: https://orcid.org/0000-0002-2903-4218)
- Guangxing Gu
- Wenjing Bao
- Ya Li (ORCID: https://orcid.org/0000-0003-4356-7042)
- Qi Jia (ORCID: https://orcid.org/0000-0003-3633-8241)
- Chenghu Hu
Institutions
- Shanghai University of Engineering Science (CN)
- Chinese Academy of Sciences (CN)
- Shanghai Institute of Organic Chemistry (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1021/acs.orglett.4c02703
- Citations
- 11
- Primary Topic
- Oxidative Organic Chemistry Reactions
- Type
- article
- Field-Weighted Citation Impact
- 2.75
Funders
- National Natural Science Foundation of China
- Chinese Academy of Sciences