Visible-Light-Mediated Ni-Catalyzed Gas-Free Carboxylation: Stereodivergent Synthesis of <i>E</i>- and <i>Z</i>-Acrylic Acids
Stereodivergent syntheses of different scaffolds from identical starting materials by switching the fewest parameters are among the most appealing synthetic technologies. Herein, a visible-light mediated Ni-catalyzed carboxylation of vinyl halides with formates has been developed, affording acrylic acids in both <i>Z</i>- and <i>E</i>-configurations from identical vinyl halides. The reaction features Ni-catalyzed gas-free carboxylation of vinyl halides by utilizing formates as a surrogate of carbon dioxide.
Authors
- Rehanguli Ruzi
- Wei Shu (ORCID: https://orcid.org/0000-0003-0890-2634)
Institutions
- Southern University of Science and Technology (CN)
- Sichuan University of Science and Engineering (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1021/acs.orglett.4c02940
- Citations
- 2
- Primary Topic
- Carbon dioxide utilization in catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.36
Funders
- National Natural Science Foundation of China
- Guangdong Science and Technology Department
- Science, Technology and Innovation Commission of Shenzhen Municipality