Disentangling the Effects of Comorbidity and Polypharmacy on Cognitive Function and Physical Frailty in Individuals With HIV

Anticholinergic and sedative burden function as a pathway through which polypharmacy and comorbidities influence physical frailty and PCD. Reducing the use of anticholinergic and sedative medications could help prevent and manage cognitive impairment and frailty in older people living with HIV.

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Publication Details

Journal
JAIDS Journal of Acquired Immune Deficiency Syndromes
Published
2024-09-09
DOI
https://doi.org/10.1097/qai.0000000000003523
Citations
4
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
2.76
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article

Disentangling the Effects of Comorbidity and Polypharmacy on Cognitive Function and Physical Frailty in Individuals With HIV

Robyn M Tamblyn, Lesley K. Fellows, Henry Ukachukwu Michael, Nancy E. Mayo et al.
4 citations
JAIDS Journal of Acquired Immune Deficiency Syndromes
HIV-related health complications and treatments
2.76
article

Disentangling the Effects of Comorbidity and Polypharmacy on Cognitive Function and Physical Frailty in Individuals With HIV

Robyn M Tamblyn, Lesley K. Fellows, Henry Ukachukwu Michael, Nancy E. Mayo, Marie‐Josée Brouillette
article en
4 citations

Abstract

Anticholinergic and sedative burden function as a pathway through which polypharmacy and comorbidities influence physical frailty and PCD. Reducing the use of anticholinergic and sedative medications could help prevent and manage cognitive impairment and frailty in older people living with HIV.

JAIDS Journal of Acquired Immune Deficiency SyndromesVol. 97(5)
Montreal Neurological Institute and Hospital (CA), McGill University Health Centre (CA), Centre for Advancing Health Outcomes (CA), Institute of Infection and Immunity (CA), McGill University (CA)
Good health and well-being
Openalex Percentile: Top 10%
HIV-related health complications and treatments
2.76
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