ctDNA Dynamics and Mechanisms of Acquired Resistance in Patients Treated with Osimertinib with or without Bevacizumab from the Randomized Phase II ETOP-BOOSTER Trial

The differential effect of treatment by smoking was not explained by TP53 mutations or other molecular alterations examined. Molecular mechanisms of acquired resistance were detected, but no novel molecular alterations were identified in the combination arm.

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Publication Details

Journal
Clinical Cancer Research
Published
2024-09-09
DOI
https://doi.org/10.1158/1078-0432.ccr-24-0932
Citations
1
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.42
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article

ctDNA Dynamics and Mechanisms of Acquired Resistance in Patients Treated with Osimertinib with or without Bevacizumab from the Randomized Phase II ETOP-BOOSTER Trial

Stephen P. Finn, Rolf A. Stahel, Ernest Nadal, Chong Ming Yeo et al.
1 citations
Clinical Cancer Research
Lung Cancer Treatments and Mutations
0.42
article

ctDNA Dynamics and Mechanisms of Acquired Resistance in Patients Treated with Osimertinib with or without Bevacizumab from the Randomized Phase II ETOP-BOOSTER Trial

Stephen P. Finn, Rolf A. Stahel, Ernest Nadal, Chong Ming Yeo, Ji‐Youn Han, Ross Andrew Soo, Roswitha Kammler, Patrick Vagenknecht, Solange Peters, Byoung Chul Cho, Christian Britschgi, Javier de Castro, Georgia Dimopoulou, Urania Dafni, Mariano Provencio, Enric Carcereny, M.Á. Sala González, Linda Coate
article en
1 citations

Abstract

The differential effect of treatment by smoking was not explained by TP53 mutations or other molecular alterations examined. Molecular mechanisms of acquired resistance were detected, but no novel molecular alterations were identified in the combination arm.

Clinical Cancer ResearchVol. 30(22)
Yonsei University (KR), National and Kapodistrian University of Athens (GR), University of Zurich (CH), Trinity College Dublin (IE), Hospital Universitario La Paz (ES), Centre Hospitalier Universitaire Vaudois (CH), Tan Tock Seng Hospital (SG), University Hospital Limerick (IE), National Cancer Center (US), Hospital de Basurto (ES), Kantonsspital Winterthur (CH), University Hospital of Zurich (CH), National University Cancer Institute, Singapore (SG), Hospital Universitario Puerta de Hierro Majadahonda (ES), Institut Català d'Oncologia (ES), National Cancer Center (KR), Frontier Science Foundation-Hellas (GR), St. James's Hospital (IE), International Breast Cancer Study Group (CH)
Good health and well-being
Openalex Percentile: Top 33%
Lung Cancer Treatments and Mutations
0.42
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