Apalutamide for non-metastatic castration-resistant prostate cancer (nmCRPC): real world data of a multicenter study

In real world more comorbid nmCRPC patients with a higher ECOG-PS and more aggressive tumors are treated with apalutamide plus ADT. Nevertheless efficacy results as well as side effects are similar in real-world compared to Spartan trial showing also a rapid, durable and deep PSA response with a median MFS of 43 months.

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Publication Details

Journal
Journal of Cancer Research and Clinical Oncology
Published
2024-09-09
DOI
https://doi.org/10.1007/s00432-024-05928-7
Citations
4
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
1.68

Funders

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article

Apalutamide for non-metastatic castration-resistant prostate cancer (nmCRPC): real world data of a multicenter study

M. Ludwig, Stefan Schultheis, Denny Varughese, P. Huwe et al.
4 citations
Journal of Cancer Research and Clinical Oncology
Prostate Cancer Treatment and Research
1.68
article

Apalutamide for non-metastatic castration-resistant prostate cancer (nmCRPC): real world data of a multicenter study

M. Ludwig, Stefan Schultheis, Denny Varughese, P. Huwe, Rainer Häußermann, Markus Thiemer, Sebastian Hollwegs, Lennart Skrobek, Anke Bartsch-Polle, Manfred Maywurm, Jost Weber, M. Vink, Axel Hegele
article en
4 citations

Abstract

In real world more comorbid nmCRPC patients with a higher ECOG-PS and more aggressive tumors are treated with apalutamide plus ADT. Nevertheless efficacy results as well as side effects are similar in real-world compared to Spartan trial showing also a rapid, durable and deep PSA response with a median MFS of 43 months.

Journal of Cancer Research and Clinical OncologyVol. 150(9)
Philipps University of Marburg (DE), Deutscher Wetterdienst (DE), Kliniken Essen-Mitte (DE), Sozialstiftung Bamberg (DE)
Philipps-Universität Marburg
Openalex Percentile: Top 15%
Prostate Cancer Treatment and Research
1.68
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Apalutamide for non-metastatic castration-resistant prostate cancer (nmCRPC): real world data of a multicenter study — M. Ludwig, Stefan Schultheis, et al. · Journal of Cancer Research and Clinical Oncology (2024) | TGRS Research Map | TGRS