Effect of lyophilized exosomes derived from umbilical cord stem cells on chronic anterior cruciate ligament cell injury
Lyophilized hUSC-EX preserve the characteristics of exosomes and can improve chronically injured (8 weeks) ACL cells. Lyophilized hUSC-EX could serve as effective and safe biomaterials that are ready to use at room temperature to enhance cell activity in patients with partial ACL tears and after remnant preservation ACL reconstruction.
Authors
- Cheng‐Chang Lu (ORCID: https://orcid.org/0000-0002-7194-9147)
- Sung‐Yen Lin (ORCID: https://orcid.org/0000-0002-4191-2183)
- Cheng-Jung Ho (ORCID: https://orcid.org/0000-0002-9049-3675)
- Yeh Ming-kung
- Hon Lok Lo
Institutions
- Kaohsiung Medical University (TW)
- Kaohsiung Municipal Hsiao-Kang Hospital (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1186/s13018-024-05029-8
- Citations
- 8
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Kaohsiung Municipal Siaogang Hospital
- Ministry of Science and Technology, Taiwan
- Kaohsiung Medical University
- Kaohsiung Medical University Chung-Ho Memorial Hospital
- National Science and Technology Council