Association of gut commensal translocation with autoantibody production in systemic lupus erythematosus
ABC transporters from gut bacteria can serve as cross-reactive antigens that may promote anti-dsDNA antibody production in genetically susceptible mice. These findings underscore the role of commensal-derived molecular mimicry and bacterial translocation in lupus pathogenesis.
Authors
- Masaki Yamamoto (ORCID: https://orcid.org/0000-0002-1311-1768)
- Yasutoshi Kido (ORCID: https://orcid.org/0000-0003-3615-2631)
- Tomonori Kamiya (ORCID: https://orcid.org/0009-0002-6970-9512)
- Masao Katsushima (ORCID: https://orcid.org/0009-0007-0033-1757)
- Yuko Nitahara
- Yoichi Nakayama (ORCID: https://orcid.org/0000-0002-8130-4350)
- Tsuneyasu Yoshida (ORCID: https://orcid.org/0000-0003-3114-8959)
- Motomu Hashimoto (ORCID: https://orcid.org/0000-0002-9241-060X)
- Hajime Yoshifuji (ORCID: https://orcid.org/0000-0001-7082-4900)
- Naoko Ohtani (ORCID: https://orcid.org/0000-0001-8934-0797)
- Ran Nakashima (ORCID: https://orcid.org/0000-0001-6247-0647)
- Yu Nakagama
- Akio Morinobu (ORCID: https://orcid.org/0000-0002-4672-638X)
- Mirei Shirakashi (ORCID: https://orcid.org/0000-0003-1135-0463)
- Ryu Watanabe (ORCID: https://orcid.org/0000-0002-1089-5296)
- Yuri Nishida (ORCID: https://orcid.org/0000-0002-7807-7927)
- Junko Satoh
- Shinji Ito
- Takashi Emori
Institutions
- Kyoto University (JP)
- Osaka Metropolitan University (JP)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1093/rheumatology/keae476
- Citations
- 3
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- Ministry of Education, Culture, Sports, Science and Technology