Cognitive impairment and depression precede increased HDL-C levels in middle-aged and older Chinese adults: cross-lagged panel analyses
Cognitive impairment and depression are associated with higher HDL-C levels, whereas higher HDL-C levels do not appear to protect against cognitive decline or depressive symptoms. These findings underscore the importance of preserving cognitive and mental health, which may lower the likelihood of cardiovascular disease and dementia. Future studies should validate these findings and develop targeted interventions tailored to specific populations.
Authors
- Cai‐Lan Hou (ORCID: https://orcid.org/0000-0002-7789-5602)
- Rui Zhou (ORCID: https://orcid.org/0000-0002-8250-9446)
- Yihui Liu (ORCID: https://orcid.org/0000-0002-6358-8687)
- Fu‐Jun Jia
- Yong‐Yi He (ORCID: https://orcid.org/0009-0003-7383-4153)
- Mu-Tong Chen
- Quan Huang
- Jia-Rong Liang
- Ming Chen (ORCID: https://orcid.org/0009-0007-3572-1579)
Institutions
- Shantou University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Shantou University Medical College (CN)
- Twelfth Guangzhou City People's Hospital (CN)
- Guangdong Academy of Medical Sciences (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1186/s12944-024-02285-9
- Citations
- 13
- Primary Topic
- Cardiovascular Health and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 5.23