Genomic and transcriptomic landscape to decipher the genetic basis of hyperpigmentation in Lanping black-boned sheep (Ovis aries)
Our findings establish the evolutionary lineage of the LPB breed from LPN and underscore the involvement of ERBB4 and ROR1 genes in melanin synthesis. These results enhance our comprehension of the molecular basis of hyperpigmentation and contribute to a more comprehensive depiction of sheep diversity.
Authors
- Weidong Deng (ORCID: https://orcid.org/0000-0002-9620-2082)
- Yuqing Chong (ORCID: https://orcid.org/0000-0001-8706-7651)
- Xiaoming He (ORCID: https://orcid.org/0000-0003-0125-6086)
- Dongmei Xi (ORCID: https://orcid.org/0000-0002-1009-363X)
- Xiaolong Tu (ORCID: https://orcid.org/0009-0001-9396-5383)
- Jieyun Hong (ORCID: https://orcid.org/0000-0002-1714-7039)
- Jiao Wu (ORCID: https://orcid.org/0009-0005-5874-5165)
- Ying Lu (ORCID: https://orcid.org/0000-0002-4770-8562)
- Zhendong Gao (ORCID: https://orcid.org/0000-0002-8816-2543)
- Heli Xiong (ORCID: https://orcid.org/0000-0003-0041-7992)
Institutions
- Kunming Institute of Zoology (CN)
- Yunnan Agricultural University (CN)
- Yunnan Animal Science and Veterinary Institute (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1186/s12864-024-10772-7
- Citations
- 7
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 2.28
Funders
- National Natural Science Foundation of China
- Chinese Academy of Sciences
- Yunnan Provincial Department of Education
- Yunnan Provincial Department of Education Science Research Fund Project
- Institute of Zoology, Chinese Academy of Sciences
- Kunming Institute of Zoology, Chinese Academy of Sciences
- Major Science and Technology Projects in Yunnan Province