<scp>HPV</scp> 16/18 <scp>E7</scp> oncoprotein detection as a promising triage strategy for <scp>HPV</scp> 16/18‐positive patients: A prospective multicenter study with a 2‐year follow up
As a triage method for high-grade CIN screening in HPV 16/18-positive patients, HPV 16/18 E7 oncoprotein demonstrated a relatively high NPV, making it suitable for clinical use in triaging HPV 16/18-positive cases and potentially reducing the colposcopic referral rate. HPV 16/18 E7 oncoprotein exhibited a preferably predictive value in determining HPV infection outcomes and disease progression.
Authors
- Xiaoping Xiao (ORCID: https://orcid.org/0000-0001-5021-9906)
- Chongdong Liu (ORCID: https://orcid.org/0000-0003-3391-9964)
- Yang Cao (ORCID: https://orcid.org/0000-0002-0058-614X)
- Tao Xu (ORCID: https://orcid.org/0000-0002-1721-561X)
- Honghui Shi (ORCID: https://orcid.org/0000-0003-3908-1322)
- Caijuan Li
- Ruoli Guan
- Junjun Yang
- Lei Zhang (ORCID: https://orcid.org/0000-0002-3825-7456)
- Lu Ye (ORCID: https://orcid.org/0009-0003-7506-2847)
- Hua Li (ORCID: https://orcid.org/0000-0003-1903-836X)
- Jin Wang (ORCID: https://orcid.org/0000-0003-4008-9284)
- Yan Li (ORCID: https://orcid.org/0000-0002-4658-2080)
- Ying Zhang (ORCID: https://orcid.org/0000-0001-6411-4486)
- Jinhui Wang (ORCID: https://orcid.org/0000-0001-6556-5887)
- Wei Wang (ORCID: https://orcid.org/0000-0002-1192-4896)
- Dandan Liang (ORCID: https://orcid.org/0000-0003-2873-7146)
- Dai Zhang
- Hui Bi
- Hong Qu
- Shuhui Song (ORCID: https://orcid.org/0000-0003-2409-8770)
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Peking Union Medical College Hospital (CN)
- Tianjin Economic-Technological Development Area (CN)
- Peking University First Hospital (CN)
Publication Details
- Journal
- International Journal of Gynecology & Obstetrics
- Published
- 2024-09-08
- DOI
- https://doi.org/10.1002/ijgo.15897
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00