Strain-specific effects of probiotics on depression and anxiety: a meta-analysis
This meta-analysis offers valuable insights into the strain-specific effects of probiotics containing Lactobacillus and Bifidobacterium species on depressive and anxiety symptoms. While our findings suggest a significant reduction in depressive symptoms based on the BDI scale favoring probiotics, the lack of significant effects observed on the HAMD, DASS, and MADRS scales underscores the complexity inherent in these conditions. It is imperative to acknowledge the mixed results across different measurement scales, indicating the need for cautious interpretation. Therefore, we advocate for a nuanced understanding of probiotics' impacts on various dimensions of mood, emphasizing the necessity for further research.
Authors
- Mohammad Javad Nasiri (ORCID: https://orcid.org/0000-0002-3279-0671)
- Mohammad Amin Aalipour (ORCID: https://orcid.org/0000-0002-1465-4756)
- Ali Kheradmand (ORCID: https://orcid.org/0000-0002-3704-9233)
- Mohadeseh Poudineh (ORCID: https://orcid.org/0000-0002-6310-8428)
- Mehdi Goudarzi (ORCID: https://orcid.org/0000-0001-6720-9341)
- Roya Mirzaei (ORCID: https://orcid.org/0000-0003-2059-0282)
- Leonardo Antonio Sechi (ORCID: https://orcid.org/0000-0003-0566-2049)
- Majid Sadeghian
- Amir Hashem Shahidi Bonjar (ORCID: https://orcid.org/0000-0002-5561-0530)
- Maryam Rahmannia (ORCID: https://orcid.org/0000-0001-8351-6587)
- Hamid Reza Aslani (ORCID: https://orcid.org/0000-0001-7142-1089)
Institutions
- University of Sassari (IT)
- Iran University of Medical Sciences (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Gut Pathogens
- Published
- 2024-09-08
- DOI
- https://doi.org/10.1186/s13099-024-00634-8
- Citations
- 36
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 8.42
Funders
- Shahid Beheshti University of Medical Sciences
- Regione Autonoma della Sardegna
- School of Medicine, Shahid Beheshti University of Medical Sciences