Sulforaphane improves post-resuscitation myocardial dysfunction by inhibiting cardiomyocytes ferroptosis via the Nrf2/IRF1/GPX4 pathway
SFN could effectively improve myocardial dysfunction after CA and resuscitation, in which the mechanism was potentially related to the inhibition of cardiomyocytes ferroptosis through the regulation of Nrf2/IRF1/GPX4 pathway.
Authors
- Shanxiang Xu
- Jiefeng Xu (ORCID: https://orcid.org/0000-0001-5597-0838)
- Xianlong Wu
- Zhongjun Zheng
- JinJiang Zhu
- Yi Mao
- Pin Lan (ORCID: https://orcid.org/0009-0000-0374-218X)
- Zhihan Mei
- Mao Zhang
Institutions
- Taizhou Second People's Hospital (CN)
- Lishui Central Hospital (CN)
- Taizhou First People's Hospital (CN)
- The First People's Hospital of Wenling (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2024-09-08
- DOI
- https://doi.org/10.1016/j.biopha.2024.117408
- Citations
- 16
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 6.43