Comparative assessment of trough and peak levels and AUC24 for amikacin in nontuberculous mycobacterial infection
In this study, we performed comparative assessment of trough/peak level, traditional clinical marker for amikacin TDM, and AUC24 value. Although AUC24 values showed poor to moderate correlation to trough/peak levels, higher AUC24 correlated with favorable clinical outcomes without additional risk of toxicity.
Authors
- Jong‐Baeck Lim (ORCID: https://orcid.org/0000-0003-0419-0422)
- John Hoon Rim (ORCID: https://orcid.org/0000-0001-6825-8479)
- Hanmil Jang
- Jaehyeok Jang
- Ji-Yeon Kim
Institutions
- Yonsei University (KR)
- Yonsei University Health System (KR)
Publication Details
- Journal
- Clinica Chimica Acta
- Published
- 2024-09-08
- DOI
- https://doi.org/10.1016/j.cca.2024.119963
- Citations
- 1
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Korea Health Industry Development Institute