Combined miR-181a-5p and Ag Nanoparticles are Effective Against Oral Cancer in a Mouse Model
Collectively, the findings demonstrate that the miR-181a-5p/AgNPs combination significantly impedes the growth and progression of oral cancer both in vitro and in vivo, highlighting a pivotal role for the β-catenin signaling pathway. This multifaceted approach holds promise as a prospective therapeutic strategy for oral cancer management in the future.
Authors
- Guohua Song (ORCID: https://orcid.org/0000-0002-0940-1252)
- Rui Xue (ORCID: https://orcid.org/0000-0002-5710-0091)
- Xiaoru Yan
- Jiping Gao (ORCID: https://orcid.org/0000-0002-8968-4423)
- Xuemin Wang (ORCID: https://orcid.org/0000-0002-6251-6745)
- Zhaoyang Chen (ORCID: https://orcid.org/0000-0002-6811-6945)
- Xiaona Song
- Litao Qin
- Guoqiang Xu
- Xiaoqi Chang
Institutions
- Shanxi Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/ijn.s458484
- Citations
- 14
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 3.99