Construction of CXCR4 Receptor-Targeted CuFeSe2 Nano Theranostic Platform and Its Application in MR/CT Dual Model Imaging and Photothermal Therapy
CuFeSe<sub>2</sub>@PA nanoparticles show potential as dual-mode imaging contrast agents for MR and CT and provide an effective means of tumor treatment through photothermal therapy. The surface modification with Plerixafor enhances the targeting ability of the nanoparticles, performing more significant efficacy and biocompatibility in the 4T1 cancer cell model. The study demonstrates that CuFeSe<sub>2</sub>@PA is a promising multifunctional theranostic platform with clinical application potential.
Authors
- Wenlu Li (ORCID: https://orcid.org/0000-0003-3938-1624)
- Wen Xiu Ren (ORCID: https://orcid.org/0000-0002-8852-4807)
- Jiong Liu (ORCID: https://orcid.org/0000-0003-2910-3882)
- Yaolin Gong
- Jian Shu (ORCID: https://orcid.org/0000-0002-7386-7217)
- Shaozhi Fu (ORCID: https://orcid.org/0000-0002-8666-4304)
- Jing Zhang (ORCID: https://orcid.org/0000-0003-0211-6202)
- Jiali Li (ORCID: https://orcid.org/0000-0001-8990-9998)
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/ijn.s470367
- Citations
- 6
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- National Natural Science Foundation of China
- Department of Science and Technology of Sichuan Province