Metformin dampens the progression of cholangiofibrosis induced by thioacetamide using deep learning
Long-term metformin use may offer protective benefits against cholangiofibrosis, partially by regulating metabolic processes and improving the tumor microenvironment.
Authors
- Chaofu Li (ORCID: https://orcid.org/0000-0002-7100-5787)
- Yating Pan (ORCID: https://orcid.org/0009-0007-3098-4521)
- Shaoqing Yu (ORCID: https://orcid.org/0000-0003-2208-4535)
- Guanzhen Yu (ORCID: https://orcid.org/0000-0001-6193-8148)
- Yating Deng
- Xiaoli Xue
- Wenlong Yu (ORCID: https://orcid.org/0000-0003-1326-7997)
- Huadong Xie
- Xinyi Liao
Institutions
- Tongji University (CN)
- Second Military Medical University (CN)
- Liuzhou General Hospital (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Beijing Academy of Artificial Intelligence (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
- Fourth Affiliated Hospital of Guangxi Medical University (CN)
- Eastern Hepatobiliary Surgery Hospital (CN)
- Tongji Hospital (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e37347
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Guangxi Zhuang Region Health Department
- Foundation for Innovative Research Groups of the National Natural Science Foundation of China