Maternal exposure to Di-n-butyl phthalate (DBP) inhibit orexin receptor 1 (OX1R) expression to prevent Sertoli cells proliferation through the AKT signaling pathway
DBP can induce Sertoli cell apoptosis through its toxicological effect by suppressing OX1R and p-AKT expression, which provide a novel insight on the role of neurotransmitter receptors.
Authors
- Min Chen (ORCID: https://orcid.org/0000-0003-4234-3178)
- Yongqing Zhang (ORCID: https://orcid.org/0000-0002-6980-1848)
- Zhiwen Xie
- Tiewen Li
- Lei Wu (ORCID: https://orcid.org/0009-0009-5104-5691)
- Juntao Jiang (ORCID: https://orcid.org/0000-0003-4294-9903)
- Xinyu Xu (ORCID: https://orcid.org/0000-0001-7328-5156)
- Yang Sun (ORCID: https://orcid.org/0009-0007-1406-7694)
Institutions
- Shanghai Jiao Tong University (CN)
- Renji Hospital (CN)
- Shanghai First People's Hospital (CN)
Publication Details
- Journal
- Toxicology Research
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1093/toxres/tfae140
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00