Effect of Tumour Necrotic Factor-α, Interleukin-17 and Interleukin-22 on the Expression of Filaggerin-2 and Hornerin: Analysis of a Three-Dimensional Psoriatic Skin Model
TNF-α, IL-17A and IL-22 have different effects on FLG2 and HRNR expression and epidermal structure formation. Furthermore, FLG2 and HRNR may play different roles in barrier formation and the pathogenesis of psoriasis.
Authors
- Tadamichi Shimizu (ORCID: https://orcid.org/0000-0002-3231-0279)
- Megumi Mizawa (ORCID: https://orcid.org/0000-0003-3348-3240)
- Keita Takemoto (ORCID: https://orcid.org/0000-0002-3036-1451)
- Teruhiko Makino (ORCID: https://orcid.org/0000-0002-0536-1679)
- Seiji Yamamoto (ORCID: https://orcid.org/0000-0003-1007-6271)
Institutions
- University of Toyama (JP)
Publication Details
- Journal
- Skin Health and Disease
- Published
- 2024-09-05
- DOI
- https://doi.org/10.1002/ski2.440
- Citations
- 3
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.60
Funders
- Japan Society for the Promotion of Science