The release of <scp>GLP</scp>‐1 from gut L cells is inhibited by low extracellular <scp>pH</scp>
GLP-1 secretion is sensitive to pHe and the buffer present. Exploiting this mechanism therapeutically may benefit patients with obesity.
Authors
- Małgorzata Cyranka
- Pawel Swietach (ORCID: https://orcid.org/0000-0002-9945-9473)
- Johanna Michl
- Heidi de Wet (ORCID: https://orcid.org/0000-0002-9871-6909)
- Kenju Shimomura (ORCID: https://orcid.org/0000-0002-1539-2532)
- Natascia Vedovato (ORCID: https://orcid.org/0000-0003-4462-5865)
- Philippa Garbutt
- Yuko Maejima
Institutions
- Fukushima Medical University (JP)
- University of Oxford (GB)
Publication Details
- Journal
- Obesity
- Published
- 2024-09-05
- DOI
- https://doi.org/10.1002/oby.24125
- Citations
- 3
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.07
Funders
- Biotechnology and Biological Sciences Research Council