Enhanced Insulin Secretion Through Upregulation of Transcription Factors by Hydroalcoholic Extract of <i>Securigera securidaca</i> Seeds in Diabetic Animal Model
HESS elicits an increase in insulin secretion through the mitigation of oxidative stress and tissue damage, as well as the modulation of gene expression related to the insulin transcription factors PDX-1 and MafA.
Authors
- Ebrahim Abbasi Oshaghi (ORCID: https://orcid.org/0000-0002-3405-562X)
- Maryam Hasani
- Heydar Tayebinia
- Shahin Alizadeh‐Fanalou (ORCID: https://orcid.org/0000-0003-0448-7074)
- Mohammad Babaei (ORCID: https://orcid.org/0000-0002-1517-7162)
- Fatemeh Mirzaei (ORCID: https://orcid.org/0000-0003-1790-7322)
- Fatemeh Khomari
- Iraj Khodadadi (ORCID: https://orcid.org/0000-0001-9048-4528)
- Elham Bahreini (ORCID: https://orcid.org/0000-0001-6823-8638)
- Bahar Kiani
- Iraj Alipourfard (ORCID: https://orcid.org/0000-0001-5164-8606)
Institutions
- Hamedan University of Medical Sciences (IR)
- Iran University of Medical Sciences (IR)
- Bu-Ali Sina University (IR)
- Urmia University (IR)
- Urmia University of Medical Sciences (IR)
- University of Silesia in Katowice (PL)
Publication Details
- Journal
- Endocrinology Diabetes & Metabolism
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/edm2.515
- Citations
- 3
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- Iran University of Medical Sciences