Preparation and evaluation of <i>Gastrodia elata</i> polysaccharide loaded electrospinning nanofiber facial mask

Abstract Facial masks available in the market are primarily made of non‐woven fabric. To extend their shelf life, preservatives, and essences are added to their ingredients. However, this practice has a significant impact on the environment and human health. As a result, consumers nowadays prefer to choose “Clean Beauty” products for their skincare routines. Herein, electrospinning technology was used to prepare a novel Janus nanofiber membrane comprising Polylactic acid/Polyvinylpyrrolidone (PLA/PVP) and Chitosan/Gelatin (CS/GEL), loaded with Gastrodia elata polysaccharide (GEP) and melatonin (MT). The Janus nanofiber facial mask is a solid mask that provides excellent moisturizing, antioxidant, and biocompatibility benefits. It can dissolve quickly and be absorbed by the skin, while the hydrophobic fiber helps slow down the rapid evaporation of water in the mask. This, combined with the Janus structure, helps delay the loss of water and allows for quick penetration, resulting in a long‐lasting moisturizing effect. Therefore, the Janus nanofiber facial mask is an ideal choice for solid facial masks and provides technical support for its application in this field.