Sex differences in functional and structural alterations of hippocampus region in chronic pain: a DTI and resting-state fMRI study
Our study indicates sex differences in structural and functional alterations in the hippocampal system in rats under chronic pain conditions. The results suggest that the hippocampus system plays an important role in the different mechanisms of chronic pain in different sexes. These findings provide reliable insights to explore the complex mechanisms underlying sex differences in chronic pain.
Authors
- Wen‐Jun Xin (ORCID: https://orcid.org/0000-0002-5380-8738)
- Dexing Luo (ORCID: https://orcid.org/0000-0001-7928-6168)
- Jia‐You Wei
- Jing-Wen Mai
- Jia‐Yan Wu
- Jie Deng (ORCID: https://orcid.org/0000-0002-2553-8822)
- Yu-Juan Duan
- Jun-Zhi Zhou
- Bo Dong
- Ting Xu
Institutions
- Sun Yat-sen University (CN)
- Fifth Affiliated Hospital of Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Huizhou Central People's Hospital (CN)
- Shanghai Center for Brain Science and Brain-Inspired Technology (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2024-09-06
- DOI
- https://doi.org/10.3389/fnins.2024.1428666
- Citations
- 3
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.03
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- Science and Technology Planning Project of Guangdong Province
- Basic and Applied Basic Research Foundation of Guangdong Province