Terpinen-4-ol suppresses proliferation and motility of cutaneous squamous cell carcinoma cells by enhancing calpain-2 expression

These findings suggest that T4O's antitumor activity in cSCC is mediated through the upregulation of calpain-2 expression and subsequent modulation of β-catenin and caspase-12.

Authors

Institutions

Publication Details

Journal
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
Published
2024-09-06
DOI
https://doi.org/10.32604/or.2024.050661
Primary Topic
Calpain Protease Function and Regulation
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Terpinen-4-ol suppresses proliferation and motility of cutaneous squamous cell carcinoma cells by enhancing calpain-2 expression

Zhirui Zeng, Dongyun Rong, Yan Yang, Yushen Su et al.
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
Calpain Protease Function and Regulation
article

Terpinen-4-ol suppresses proliferation and motility of cutaneous squamous cell carcinoma cells by enhancing calpain-2 expression

Zhirui Zeng, Dongyun Rong, Yan Yang, Yushen Su, Honguan Lu
article en

Abstract

These findings suggest that T4O's antitumor activity in cSCC is mediated through the upregulation of calpain-2 expression and subsequent modulation of β-catenin and caspase-12.

Oncology Research Featuring Preclinical and Clinical Cancer TherapeuticsVol. 33(3)
Guiyang Medical University (CN), Affiliated Hospital of Guizhou Medical University (CN)
Zero hunger
Openalex Percentile: Top 84%
Calpain Protease Function and Regulation
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.