Photosono-Responsive BiOCl@Bi<sub>2</sub>S<sub>3</sub> Heterostructure for Rapid Bacteria Killing
The emergence of drug-resistant bacteria poses a serious threat to human health and safety, thus requiring the exploration of effective antibacterial strategies. Herein, BiOCl nanosheets were synthesized using a polyol solvothermal method, and then Bi2S3 nanorods were in situ grown on the surface of BiOCl by doping S element with thioacetamide, forming BiOCl@Bi2S3 composites. The experimental results show that in comparison to BiOCl nanosheets, the BiOCl@Bi2S3 composite enhances the photodynamic, sonodynamic, and thermal effects under the combined action of ultrasound (US) and 808 nm near-infrared (NIR) light to generate more radical oxygen species (ROS) and induces local hyperthermia. Therefore, under the conditions of photoacoustic combination for 20 min, the composite material has excellent rapid antibacterial effect of 99.7% against Staphylococcus aureus and 100.0% against Escherichia coli. Additionally, the BiOCl@Bi2S3 composite has a good biocompatibility with NIH-3T3 cells. This study will provide insights into the design of efficient and safe antibacterial materials.
Authors
- Xiangmei Liu (ORCID: https://orcid.org/0000-0002-6469-2363)
- Jie Shen (ORCID: https://orcid.org/0000-0001-6895-7413)
- Congyang Mao (ORCID: https://orcid.org/0000-0002-0499-3674)
- Zhenxing Yang (ORCID: https://orcid.org/0000-0001-5572-6798)
- Cuihong Chen (ORCID: https://orcid.org/0000-0001-9175-9554)
- Yufeng Zheng (ORCID: https://orcid.org/0000-0002-7402-9979)
- Yu Zhang (ORCID: https://orcid.org/0000-0003-0978-2363)
- Wenxiang Li (ORCID: https://orcid.org/0000-0003-2931-2692)
- Chaofeng Wang (ORCID: https://orcid.org/0009-0004-3444-802X)
- Shuilin Wu (ORCID: https://orcid.org/0000-0002-1270-1870)
- Qian Ran
Institutions
- Huanggang Normal University (CN)
- Hebei University of Technology (CN)
- Peking University (CN)
- Peking University Shenzhen Hospital (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Hubei University (CN)
Publication Details
- Journal
- ACS Applied Nano Materials
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1021/acsanm.4c04459
- Citations
- 7
- Primary Topic
- Advanced Photocatalysis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.72
Funders
- National Natural Science Foundation of China
- National Science Fund for Distinguished Young Scholars
- National Natural Science Foundation of China-Guangdong Joint Fund