Membrane RRM2-positive cells represent a malignant population with cancer stem cell features in intrahepatic cholangiocarcinoma
RRM2 had an alternative cell membrane localization. The membrane RRM2-positive iCCA cells represented a malignant subpopulation with cancer stem cell features.
Authors
- Jianing Yan (ORCID: https://orcid.org/0000-0002-8781-9021)
- Xiujun Cai (ORCID: https://orcid.org/0000-0002-6457-0577)
- Stéphanie Roessler (ORCID: https://orcid.org/0000-0002-5333-5942)
- Nachuan Zhang
- Danduo Wei
- Junfang Ji (ORCID: https://orcid.org/0000-0002-3071-6494)
- Liping Mao (ORCID: https://orcid.org/0000-0002-0857-3896)
- Jianjuan Zhang
- Shuting Xue
- Saiyong Zhu
- Yongzhi Zhao (ORCID: https://orcid.org/0000-0002-2509-8089)
- Niya Liu
- Lei Zhao (ORCID: https://orcid.org/0000-0002-5421-6101)
- Yifan Wang (ORCID: https://orcid.org/0009-0003-9385-5277)
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Sir Run Run Shaw Hospital (CN)
- Shandong Tumor Hospital (CN)
- Shandong First Medical University (CN)
- Zhejiang Gongshang University (CN)
Publication Details
- Journal
- Journal of Experimental & Clinical Cancer Research
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1186/s13046-024-03174-w
- Citations
- 2
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- Deutsche Forschungsgemeinschaft
- National Natural Science Foundation of China
- Deutsche Krebshilfe
- Fundamental Research Funds for the Central Universities