Messenger ribonucleic acids (mRNA) technology for future applications in cancer treatment

Technological developments in medicine have made it possible to treat certain diseases, such as cancer, at the root level of transcription and translation with recent development in clinical pharmacology and therapeutics. The world has learned about messenger ribonucleic acids (mRNA) technology in the last two years. In that time, it has shown how quickly it can respond to situations and has almost limitless potential for future applications in the treatment of cancer. The genetic instructions or recipes that guide cells on how to use their own machinery to build proteins are carried by a molecule called mRNA. Lipid nanoparticles, an increasingly common means of delivering genes that can contain both proteins and nucleic acids, enclose the mRNA in a protective bubble that allows it to circulate freely throughout the cells. Once inside, human cells use the mRNA as a set of instructions to produce proteins that attach to the unique areas of the pathogen, or antigens. The immune system promptly produces antibodies and T-cells as defenses when it perceives foreign antigens as invaders, fortifying the system's defenses against subsequent attacks. As a result, if and when the real virus manifests, the body might be able to recognize the warning signal it sends out to help guard against infection and illness. The study demonstrated how mRNA can be a powerful tool for developing vaccines and diseases treatments, allowing human cells to put forth a lot of effort in generating proteins that trigger an immune response that defends against illnesses and preserves human organs, which marks a significant milestone in science and demonstrates the adaptability and versatility of mRNA technology for known and unknown diseases treatments.

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Institutions

Publication Details

Journal
Diagnostics and Therapeutics
Published
2024-09-06
DOI
https://doi.org/10.55976/dt.32024127820-31
Citations
3
Primary Topic
RNA and protein synthesis mechanisms
Type
article
Field-Weighted Citation Impact
0.70
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article

Messenger ribonucleic acids (mRNA) technology for future applications in cancer treatment

Ugochukwu Okwudili Matthew, Kafayat Motomori Bakare, Emmanuel Adebola Adebanjo, Victoria Enemona Oseni
3 citations
Diagnostics and Therapeutics
RNA and protein synthesis mechanisms
0.70
article

Messenger ribonucleic acids (mRNA) technology for future applications in cancer treatment

Ugochukwu Okwudili Matthew, Kafayat Motomori Bakare, Emmanuel Adebola Adebanjo, Victoria Enemona Oseni
article en
3 citations

Abstract

Technological developments in medicine have made it possible to treat certain diseases, such as cancer, at the root level of transcription and translation with recent development in clinical pharmacology and therapeutics. The world has learned about messenger ribonucleic acids (mRNA) technology in the last two years. In that time, it has shown how quickly it can respond to situations and has almost limitless potential for future applications in the treatment of cancer. The genetic instructions or recipes that guide cells on how to use their own machinery to build proteins are carried by a molecule called mRNA. Lipid nanoparticles, an increasingly common means of delivering genes that can contain both proteins and nucleic acids, enclose the mRNA in a protective bubble that allows it to circulate freely throughout the cells. Once inside, human cells use the mRNA as a set of instructions to produce proteins that attach to the unique areas of the pathogen, or antigens. The immune system promptly produces antibodies and T-cells as defenses when it perceives foreign antigens as invaders, fortifying the system's defenses against subsequent attacks. As a result, if and when the real virus manifests, the body might be able to recognize the warning signal it sends out to help guard against infection and illness. The study demonstrated how mRNA can be a powerful tool for developing vaccines and diseases treatments, allowing human cells to put forth a lot of effort in generating proteins that trigger an immune response that defends against illnesses and preserves human organs, which marks a significant milestone in science and demonstrates the adaptability and versatility of mRNA technology for known and unknown diseases treatments.

Diagnostics and Therapeutics
Universidade Federal de Lavras (BR), Department of Public Health (US), University of Salford (GB)
Openalex Percentile: Top 30%
RNA and protein synthesis mechanisms
0.70
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