Safety and efficacy of a novel dexmedetomidine nasal spray for pre-anesthetic sedation in children: a randomized, double-blind, placebo-controlled trial

This novel dexmedetomidine nasal spray presented effective pre-anesthetic sedation in children with a tolerable safety profile.

Authors

Xiaohua Zou (ORCID: https://orcid.org/0000-0001-5287-9414)
Zhibin Zhao (ORCID: https://orcid.org/0000-0002-8994-3106)
Quanren Wang
Jianling Bai (ORCID: https://orcid.org/0000-0002-9845-5198)
Hua‐Cheng Liu
Rong Jiang (ORCID: https://orcid.org/0000-0003-4062-5550)
Fang Wang (ORCID: https://orcid.org/0000-0002-9256-502X)
Xiaoling Wang (ORCID: https://orcid.org/0000-0003-2136-7410)
Jianmin Zhang (ORCID: https://orcid.org/0000-0002-3184-1502)
Jiaqiang Zhang (ORCID: https://orcid.org/0000-0002-4329-784X)
Haichun Ma (ORCID: https://orcid.org/0000-0002-8467-5421)
Ping Zhao
Xingrong Song (ORCID: https://orcid.org/0000-0002-2818-2622)
Jia Gao (ORCID: https://orcid.org/0000-0001-6203-209X)
Xiaoqing Chai (ORCID: https://orcid.org/0000-0002-6176-6435)
N. Zhou (ORCID: https://orcid.org/0000-0002-1775-2511)
Saiying Wang (ORCID: https://orcid.org/0000-0003-0083-5764)

Central South University (CN)
Guiyang Medical University (CN)
Capital Medical University (CN)
Jilin University (CN)
Wenzhou Medical University (CN)
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
Affiliated Hospital of Guizhou Medical University (CN)
First Hospital of Jilin University (CN)
The First People’s Hospital of Lianyungang (CN)
Anhui Provincial Hospital (CN)
Henan Provincial People's Hospital (CN)
Beijing Children’s Hospital (CN)
Jiangsu Hengrui Medicine (China) (CN)
Third Xiangya Hospital (CN)
Nanjing Medical University (CN)
China Medical University (CN)
Guangzhou Medical University (CN)