A comprehensive map of the aging blood methylome in humans
This study represents the largest investigation to date of genome-wide DNA methylation changes and aging in a single tissue, providing valuable insights into primary molecular changes relevant to chronological and biological aging.
Authors
- Kirsten Seale (ORCID: https://orcid.org/0000-0003-3048-7983)
- Nir Eynon (ORCID: https://orcid.org/0000-0003-4046-8276)
- Sarah Voisin (ORCID: https://orcid.org/0000-0002-4074-7083)
- Andrew E. Teschendorff (ORCID: https://orcid.org/0000-0001-7410-6527)
- Alexander P. Reiner
Institutions
- University of Washington (US)
- Australian Regenerative Medicine Institute (AU)
- Shanghai Institute of Nutrition and Health (CN)
- CRUK Lung Cancer Centre of Excellence (GB)
- University College London (GB)
- Monash University (AU)
- Victoria University (AU)
Publication Details
- Journal
- Genome biology
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1186/s13059-024-03381-w
- Citations
- 14
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 3.27
Funders
- Jackson State University
- Mississippi State Department of Health
- Medical Research Council
- National Health and Medical Research Council
- National Heart, Lung, and Blood Institute
- National Institute on Minority Health and Health Disparities