Peri-domestic entomological surveillance using private traps allows detection of dengue virus in Aedes albopictus during an autochthonous transmission event in mainland France, late summer 2023
While locally-acquired dengue virus (DENV) human infections occur in mainland France since 2010, data to identify the mosquito species involved and to trace the virus are frequently lacking. Supported by a local network gathering public health agencies and research laboratories, we analysed, in late summer 2023, mosquitoes from privately-owned traps within a French urban neighbourhood affected by a dengue cluster. The cluster, in Auvergne-Rhône-Alpes, comprised three cases, including two autochthonous ones. Upon return from a recent visit to the French Caribbean Islands, the third case had consulted healthcare because of dengue-compatible symptoms, but dengue had not been recognised. For the two autochthonous cases, DENV-specific antibodies in serum or a positive quantitative PCR for DENV confirmed DENV infection. The third case had anti-flavivirus IgMs. No DENV genetic sequences were obtained from affected individuals but <i>Aedes albopictus</i> mosquitoes trapped less than 200 m from the autochthonous cases' residence contained DENV. Genetic data from the mosquito-derived DENV linked the cluster to the 2023-2024 dengue outbreak in the French Caribbean Islands. This study highlights the importance of raising mosquito-borne disease awareness among healthcare professionals. It demonstrates <i>Ae. albopictus</i> as a DENV vector in mainland France and the value of private mosquito traps for entomo-virological surveillance.
Authors
- Gilda Grard (ORCID: https://orcid.org/0000-0002-6088-2581)
- Christophe Bellet
- Sara Moutailler (ORCID: https://orcid.org/0000-0003-3010-6968)
- Barbara Viginier (ORCID: https://orcid.org/0000-0002-0733-8974)
- Élise Brottet (ORCID: https://orcid.org/0000-0003-1892-284X)
- Albin Fontaine (ORCID: https://orcid.org/0000-0001-6869-6516)
- Marie-Claire Paty (ORCID: https://orcid.org/0000-0002-4640-2617)
- Vincent Raquin (ORCID: https://orcid.org/0000-0001-6814-4199)
- Maxime Ratinier (ORCID: https://orcid.org/0000-0003-2271-3549)
- Raphaëlle Klitting (ORCID: https://orcid.org/0000-0002-7777-0308)
- Nathalie Ragozin
- Frédérick Arnaud (ORCID: https://orcid.org/0000-0001-6893-9848)
- Xavier de Lamballerie
- Violaine Bonnefoux
- Armelle Mercurol
- Clémence Galon
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Inserm (FR)
- École Pratique des Hautes Études (FR)
- École Nationale Vétérinaire d'Alfort (FR)
- Aix-Marseille Université (FR)
- Université Paris Sciences et Lettres (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Santé Publique France (FR)
- Institut de Médecine Tropicale du Service de Santé des Armées (FR)
- Agence Régionale de Santé Ile-de-France (FR)
- Institut thématique Santé Publique (FR)
- Institut de Recherche pour le Développement (FR)
Publication Details
- Journal
- Eurosurveillance
- Published
- 2024-09-05
- DOI
- https://doi.org/10.2807/1560-7917.es.2024.29.36.2400195
- Citations
- 5
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Equipex
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- Centre National de la Recherche Scientifique
- Université Claude Bernard Lyon 1
- École Normale Supérieure de Lyon
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement