Coronary Arteries Spasm After Administration of Atropine for Premedication

We report a case of severe retrosternal pain in 28-year-old patient with no cardiovascular diseases in history, developed after intravenous administration of 0.5 atropine sulfate 0.1 % solution for the purpose of premedication before the planned operation for endometrioid ovarian cysts and managed with nitrates spray. Taking into account the clinical picture, transient ischemic changes in the electrocardiogram and the association with the administration of atropine, it can be assumed that the patient had a spasm of the coronary arteries caused by the administration of atropine. There are only a very small number of descriptions of similar observations in the literature, which are also discussed in the article.

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Publication Details

Journal
Russian Sklifosovsky Journal Emergency Medical Care
Published
2024-09-05
DOI
https://doi.org/10.23934/2223-9022-2024-13-2-299-304
Primary Topic
Cardiac, Anesthesia and Surgical Outcomes
Type
article
Field-Weighted Citation Impact
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article

Coronary Arteries Spasm After Administration of Atropine for Premedication

M. A. Fedin, A. F. Farzutdinov, А. З. Хашукоева, Kseniia A. Eruslanova et al.
Russian Sklifosovsky Journal Emergency Medical Care
Cardiac, Anesthesia and Surgical Outcomes
article

Coronary Arteries Spasm After Administration of Atropine for Premedication

M. A. Fedin, A. F. Farzutdinov, А. З. Хашукоева, Kseniia A. Eruslanova, Olga Tkacheva, A. M. Shatov, A. Yu. Shchedrina, K. O. Orunbekova, L. P. Prokhorova, E. A. Rodnyanskaya, Nihal Fathi, S. R. Gilyarevsky
article en

Abstract

We report a case of severe retrosternal pain in 28-year-old patient with no cardiovascular diseases in history, developed after intravenous administration of 0.5 atropine sulfate 0.1 % solution for the purpose of premedication before the planned operation for endometrioid ovarian cysts and managed with nitrates spray. Taking into account the clinical picture, transient ischemic changes in the electrocardiogram and the association with the administration of atropine, it can be assumed that the patient had a spasm of the coronary arteries caused by the administration of atropine. There are only a very small number of descriptions of similar observations in the literature, which are also discussed in the article.

Russian Sklifosovsky Journal Emergency Medical CareVol. 13(2)
Pirogov Russian National Research Medical University (RU)
Openalex Percentile: Top 73%
Cardiac, Anesthesia and Surgical Outcomes
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