p16 Immunohistochemical Patterns in Triple-Negative Breast Cancer: Clinical and Genomic Similarities of the p16 Diffuse Pattern to pRB Deficiency
In TNBC, the diffuse p16 pattern shows clinical and genomic similarities to pRB-deficient tumors, suggesting shared characteristics. This suggests that p16 IHC testing may provide new therapeutic approaches, underscoring its potential clinical importance.
Authors
- Woo Chan Park (ORCID: https://orcid.org/0000-0002-1265-1981)
- Jun Kang (ORCID: https://orcid.org/0000-0002-7967-0917)
- Jieun Lee (ORCID: https://orcid.org/0000-0002-2656-0650)
- Miseon Lee (ORCID: https://orcid.org/0000-0002-6385-7621)
- Ahwon Lee (ORCID: https://orcid.org/0000-0002-2523-9531)
- Byung-Ock Choi
Institutions
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Pathobiology
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1159/000541299
- Citations
- 1
- Primary Topic
- Cancer-related Molecular Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- National Research Foundation
- National Research Foundation of Korea