Efficacy of an intensive multimodal rehabilitation program in adult patients affected by complex regional pain syndrome type 1 (CRPS 1): a randomized controlled trial

The Complex Regional Pain Syndrome (CRPS) type 1 is a complex nosological entity, mostly with post-traumatic genesis (osteo-myoarticular traumas of various nature, in particular bone fractures, especially in the case of fractures treated conservatively with immobilisation in plaster), characterised by intense painful joint and peri-articular symptoms that can be extremely disabling, with pain frequently refractory to the usual therapeutic strategies - pharmacological and otherwise - and with consequent importantalgo-functional limitations and sometimes severe reduction in the person’s quality of life. The aim of the present clinical study is to verify the role of Physical and Rehabilitation Therapy and the related ndividual Rehabilitation Project in the treatment of patients suffering from Complex Regional Pain Syndrome type 1 (CRPS 1) and in particular to evaluate the efficacy of a specific intensive and multimodal Rehabilitation Program in adult patients suffering from CRPS 1.