Diagnostic potential of combining plasma biomarkers of tissue damage and inflammation in pediatric TB
Our data suggest that combining the analyses of multiple biomarkers in plasma has the potential to enhance diagnosis of TB in children and, thus, warrants additional investigation. In particular, the diagnostic potential of IFN-γ/MCP-1 ratios should be further explored in larger pediatric cohorts.
Authors
- Marc Tebruegge (ORCID: https://orcid.org/0000-0003-4007-0807)
- Begoña Santiago (ORCID: https://orcid.org/0000-0002-4125-0423)
- Mar Santos (ORCID: https://orcid.org/0000-0003-1986-9016)
- Andrea López-Suárez
- María José Serrano (ORCID: https://orcid.org/0000-0003-0298-9054)
- Ángel Hernández‐Bartolomé
- Jesús Saavedra‐Lozano (ORCID: https://orcid.org/0000-0001-5971-011X)
- Elena María Rincón‐López (ORCID: https://orcid.org/0000-0002-0982-1636)
- Luz María Medrano
- Alicia Hernanz‐Lobo (ORCID: https://orcid.org/0000-0002-9560-9104)
- David Aguilera‐Alonso (ORCID: https://orcid.org/0000-0003-1017-2386)
- Marı́a Luisa Navarro
- José Luis Jiménez Fuentes
Institutions
- Royal Children's Hospital (AU)
- Instituto de Salud Carlos III (ES)
- Hospital General Universitario Gregorio Marañón (ES)
- Centro Nacional de Microbiologia (ES)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Hospital Universitario de La Princesa (ES)
- Medical Research Network (US)
- University College London (GB)
Publication Details
- Journal
- Journal of Microbiology Immunology and Infection
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1016/j.jmii.2024.07.011
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00