Small Molecule Decoy of Amyloid-β Aggregation Blocks Activation of Microglia-Like Cells
Our findings open the possibility that the molecular decoys of Aβ aggregation may block microglial activation by Aβ40 and Aβ42 in addition to blocking neurotoxicity as shown previously.
Authors
- Sho Oasa (ORCID: https://orcid.org/0000-0003-3800-590X)
- Marianne Schultzberg (ORCID: https://orcid.org/0000-0002-8314-0927)
- Gefei Chen (ORCID: https://orcid.org/0000-0002-5543-5963)
- Lars Terenius
Institutions
- Karolinska Institutet (SE)
- Institute of Neurobiology (BG)
Publication Details
- Journal
- Journal of Alzheimer s Disease
- Published
- 2024-09-04
- DOI
- https://doi.org/10.3233/jad-231399
- Citations
- 2
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.49
Funders
- Stiftelsen för Strategisk Forskning
- Vetenskapsrådet
- Demensfonden
- National Cancer Institute