“Synthetic” DSC Perfusion MRI with Adjustable Acquisition Parameters in Brain Tumors Using Dynamic Spin-and-Gradient-Echo Echoplanar Imaging
Dynamic SAGE-EPI allows for simultaneous generation of CBV-optimized and PSR-optimized DSC data with one acquisition and a single contrast injection, facilitating the use of a single perfusion protocol for all DSC applications. This approach may also be useful for comparisons of perfusion metrics across heterogeneous multicenter datasets, as it facilitates post-hoc harmonization.
Authors
- Noriko Salamon (ORCID: https://orcid.org/0000-0002-3520-9467)
- Richard G. Everson (ORCID: https://orcid.org/0000-0003-2809-3061)
- Benjamin M. Ellingson (ORCID: https://orcid.org/0000-0002-2764-6640)
- Whitney B. Pope (ORCID: https://orcid.org/0000-0003-4803-1992)
- Jingwen Yao (ORCID: https://orcid.org/0000-0002-8828-1841)
- Francesco Sanvito (ORCID: https://orcid.org/0000-0003-3379-9958)
- Nicholas S. Cho (ORCID: https://orcid.org/0000-0002-8686-0575)
- Timothy F. Cloughesy (ORCID: https://orcid.org/0000-0002-8656-7483)
- Catalina Raymond (ORCID: https://orcid.org/0000-0003-2757-439X)
- Donatello Telesca (ORCID: https://orcid.org/0000-0003-0773-451X)
- Jerrold L. Boxerman (ORCID: https://orcid.org/0000-0001-5972-4597)
Institutions
- University of California, Los Angeles (US)
- Brown University (US)
- Los Angeles Medical Center (US)
- Neurobehavioral Systems (US)
- Samueli Institute (US)
- Imaging Center (US)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2024-09-06
- DOI
- https://doi.org/10.3174/ajnr.a8475
- Citations
- 2
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.81