Viral load suppression and HIV-1 drug resistance mutations in persons with HIV on TLD/TAFED in Zambia
Our findings show that viral suppression was high after switching to TLD/TAFED; but lower than the last 95% target of the UNAIDS. Adherence to antiretroviral therapy was a significant correlate of VL suppression. We, therefore, recommend prompt switching of PWH to TLD/TAFED regimen and close monitoring to enhance adherence to therapy.
Authors
- Sepiso K. Masenga (ORCID: https://orcid.org/0000-0003-4376-5831)
- Benson M. Hamooya (ORCID: https://orcid.org/0000-0003-1385-0998)
- Emmanuel Luwaya (ORCID: https://orcid.org/0000-0001-9518-2422)
- Lackson Mwape (ORCID: https://orcid.org/0000-0002-8989-6856)
- Kaole Bwalya (ORCID: https://orcid.org/0009-0007-1924-6819)
- Chileleko Siakabanze (ORCID: https://orcid.org/0000-0001-6915-1788)
Institutions
- Mulungushi University (ZM)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1371/journal.pone.0308869
- Citations
- 2
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.78
Funders
- American Heart Association
- World Health Organization
- National Institutes of Health
- Fogarty International Center
- National Institute of Diabetes and Digestive and Kidney Diseases