Effectiveness of Disease-Modifying Treatment on Spinal Cord Lesion Formation in Relapse-Onset Multiple Sclerosis: An MSBase Registry Study
A potential discrepancy exists in the effect of hDMTs over lDMTs in preventing spinal cord lesions versus brain lesions and relapses. While hDMTs provided a significant reduction for the latter when compared to lDMTs, there was no significant reduction in new spinal cord lesions.
Authors
- Jeannette Lechner‐Scott (ORCID: https://orcid.org/0000-0002-3850-447X)
- Daniele Spitaleri (ORCID: https://orcid.org/0009-0009-8290-6781)
- Davide Maimone (ORCID: https://orcid.org/0000-0003-1906-7953)
- Tomáš Kalinčík (ORCID: https://orcid.org/0000-0003-3778-1376)
- Daniël Kreiter (ORCID: https://orcid.org/0000-0003-0954-1834)
- Samia Joseph Khoury (ORCID: https://orcid.org/0000-0003-3198-6063)
- Matteo Foschi (ORCID: https://orcid.org/0000-0002-0321-7155)
- Francesco Patti (ORCID: https://orcid.org/0000-0002-6923-0846)
- Oliver Gerlach (ORCID: https://orcid.org/0000-0003-1565-1458)
- Serkan Özakbaş (ORCID: https://orcid.org/0000-0003-2140-4103)
- Andrea Surcinelli (ORCID: https://orcid.org/0000-0003-3779-0934)
- Bassem Yamout
- Raymond Hupperts (ORCID: https://orcid.org/0000-0003-2106-2158)
Institutions
- The Royal Melbourne Hospital (AU)
- İzmir University of Economics (TR)
- The University of Melbourne (AU)
- University of L'Aquila (IT)
- Harley-Davidson (United States) (US)
- Maastricht University Medical Centre (NL)
- John Hunter Hospital (AU)
- Maastricht University (NL)
- Hunter Medical Research Institute (AU)
- Ospedale "Santa Maria delle Croci" di Ravenna (IT)
- American University of Beirut Medical Center (LB)
- Azienda Ospedaliera S.Giuseppe Moscati (IT)
- Policlinico Universitario di Catania (IT)
- Zuyderland Medisch Centrum (NL)
- Ospedale Cannizzaro (IT)
Publication Details
- Journal
- CNS Drugs
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1007/s40263-024-01115-x
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sanofi
- Biogen
- Teva Pharmaceutical Industries
- Università di Catania