Lipocalin-2 aggravates blood-brain barrier dysfunction after intravenous thrombolysis by promoting endothelial cell ferroptosis via regulating the HMGB1/Nrf2/HO-1 pathway
LCN2 aggravated BBB disruption after thrombolysis by promoting endothelial cell ferroptosis via regulating the HMGB1/Nrf2/HO-1 pathway, this may provide a promising therapeutic target for the prevention of HT after IVT.
Authors
- Yang Qu (ORCID: https://orcid.org/0000-0001-8598-3517)
- Ruoyu Zhao (ORCID: https://orcid.org/0000-0002-6232-5770)
- Qianyan He
- Zhen‐Ni Guo (ORCID: https://orcid.org/0000-0002-8922-3862)
- Yi Yang (ORCID: https://orcid.org/0000-0002-9729-8522)
- Shengyu Zhou (ORCID: https://orcid.org/0000-0002-6254-2986)
- Shu-Yan Pang
- Jie Liu (ORCID: https://orcid.org/0009-0006-5054-4550)
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Redox Biology
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1016/j.redox.2024.103342
- Citations
- 38
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 14.03