Increased risk of cardiac arrhythmia in Hailey-Hailey disease patients
This study reveals that HHD is associated with an increased risk of arrhythmia and represents the first data of any extracutaneous comorbidity in HHD. Thus, HHD may be a systemic disease. Our findings also shed light on the importance of the Golgi apparatus' Ca2+/Mn2+ homeostasis in common heart disease.
Authors
- William Jebril
- Henrik Larsson (ORCID: https://orcid.org/0000-0002-6851-3297)
- Jakob D. Wikström (ORCID: https://orcid.org/0000-0002-4287-1774)
- Philip Curman (ORCID: https://orcid.org/0000-0003-2051-8491)
- Martin Cederlöf (ORCID: https://orcid.org/0000-0002-1470-1639)
- Daniel Andersson (ORCID: https://orcid.org/0000-0003-4548-702X)
- Etty Bachar-Wikström (ORCID: https://orcid.org/0000-0002-3283-6721)
Institutions
- Karolinska University Hospital (SE)
- Örebro University (SE)
- Karolinska Institutet (SE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1371/journal.pone.0309482
- Primary Topic
- Genetic and rare skin diseases.
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jeanssons Stiftelser
- Tore Nilsons Stiftelse för Medicinsk Forskning
- Svenska Sällskapet för Medicinsk Forskning
- Vetenskapsrådet
- Marcus och Amalia Wallenbergs minnesfond
- LEO Fondet
- HudFonden