Comprehensive modulatory effects of whole grain consumption on immune-mediated inflammation in middle-aged and elderly community residents: A real-world randomized controlled trial
The findings suggest that the anti-inflammatory effects of whole grain consumption in middle-aged and elderly populations are mediated by targeting specific CD4<sup>+</sup> T cell subsets, in addition to modulating both upstream short-chain fatty acid composition and downstream expression of the pro-inflammatory cytokines IL-22 and IL-23.
Authors
- Yisi Wang (ORCID: https://orcid.org/0000-0003-1306-4444)
- Zhiwen Ge (ORCID: https://orcid.org/0000-0003-2696-4281)
- Cheng Li
- Bingjie Ding (ORCID: https://orcid.org/0000-0001-8158-3743)
- Yanxia Bi (ORCID: https://orcid.org/0000-0001-7705-4777)
- Zhongxin Hong (ORCID: https://orcid.org/0000-0002-9070-046X)
- Nan Wang (ORCID: https://orcid.org/0009-0005-7049-9980)
- Congcong Wang (ORCID: https://orcid.org/0000-0002-6471-3865)
- Yuxia Wang (ORCID: https://orcid.org/0000-0002-6095-1030)
- Yaru Li (ORCID: https://orcid.org/0000-0003-1647-6743)
- Xinli Yang
- Zebin Peng
- Jia Wang (ORCID: https://orcid.org/0000-0002-2330-8505)
Institutions
- Capital Medical University (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- Redox Biology
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1016/j.redox.2024.103337
- Citations
- 14
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 4.57
Funders
- Capital Medical University
- Beijing Friendship Hospital, Capital Medical University