Finite element model reveals the involvement of cartilage endplate in quasi-static biomechanics of intervertebral disc degeneration
Glycosaminoglycan content and CEP permeability are critical to the fluid-dependent viscoelastic response of intervertebral discs. Our findings suggest that CEP contributes to disc degeneration under daily loading conditions.
Authors
- Xinning Mao
- Du He (ORCID: https://orcid.org/0000-0002-6358-3130)
- Yujun Zhang (ORCID: https://orcid.org/0000-0003-0150-6110)
- Hongting Jin
- Liangping Zhang (ORCID: https://orcid.org/0000-0002-8530-2053)
- Dong Wang (ORCID: https://orcid.org/0000-0001-6267-8819)
- Hang Zhu
- Wei Zhang (ORCID: https://orcid.org/0000-0002-3933-0109)
- Hao Pan (ORCID: https://orcid.org/0000-0002-9140-1912)
- Chengyue Zhu (ORCID: https://orcid.org/0000-0001-9653-7336)
- Wei Cheng (ORCID: https://orcid.org/0009-0000-6677-3119)
- Yanli Pan
Institutions
- Zhejiang Chinese Medical University (CN)
- Zhejiang Hospital (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e37524
- Citations
- 3
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 1.27
Funders
- Science and Technology Program of Zhejiang Province